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Gene drive is the practice of "stimulating biased inheritance of particular genes to alter entire populations." It has been proposed as a technique for changing wild populations of harmful organisms such as mosquitos to be less dangerous. In addition to combating diseases spread by insects, gene drives might be used to control invasive species or to eliminate herbicide- or pesticide resistance. Possible alterations include adding, disrupting, or modifying genes, including some that reduce reproductive capacity and may cause a population crash. Synthetic gene drives based on homing endonucleases were first proposed in 2003.== History ==Austin Burt, an evolutionary geneticist at Imperial College London,(Austin Burt profile ) first outlined the possibility of building gene drives based on natural "selfish" homing endonuclease genes. Researchers had already shown that these “selfish” genes could spread rapidly through successive generations. Burt suggested that gene drives might be used to prevent a mosquito population from transmitting the malaria parasite or crash a mosquito population. Gene drives based on homing endonucleases have been demonstrated in the laboratory in transgenic populations of mosquitoes and fruit flies. These enzymes could be used to drive alterations through wild populations.
Gene drive is the practice of "stimulating biased inheritance of particular genes to alter entire populations." It has been proposed as a technique for changing wild populations of harmful organisms such as mosquitos to be less dangerous. In addition to combating diseases spread by insects, gene drives might be used to control invasive species or to eliminate herbicide- or pesticide resistance.〔〔 Possible alterations include adding, disrupting, or modifying genes, including some that reduce reproductive capacity and may cause a population crash.〔〔 Synthetic gene drives based on homing endonucleases were first proposed in 2003.
== History ==
Austin Burt, an evolutionary geneticist at Imperial College London,〔(Austin Burt profile )〕 first outlined the possibility of building gene drives based on natural "selfish" homing endonuclease genes.〔 Researchers had already shown that these “selfish” genes could spread rapidly through successive generations. Burt suggested that gene drives might be used to prevent a mosquito population from transmitting the malaria parasite or crash a mosquito population. Gene drives based on homing endonucleases have been demonstrated in the laboratory in transgenic populations of mosquitoes and fruit flies. These enzymes could be used to drive alterations through wild populations.〔
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
■ウィキペディアで「Gene drive is the practice of "stimulating biased inheritance of particular genes to alter entire populations." It has been proposed as a technique for changing wild populations of harmful organisms such as mosquitos to be less dangerous. In addition to combating diseases spread by insects, gene drives might be used to control invasive species or to eliminate herbicide- or pesticide resistance. Possible alterations include adding, disrupting, or modifying genes, including some that reduce reproductive capacity and may cause a population crash. Synthetic gene drives based on homing endonucleases were first proposed in 2003.== History ==Austin Burt, an evolutionary geneticist at Imperial College London,(Austin Burt profile ) first outlined the possibility of building gene drives based on natural "selfish" homing endonuclease genes. Researchers had already shown that these “selfish” genes could spread rapidly through successive generations. Burt suggested that gene drives might be used to prevent a mosquito population from transmitting the malaria parasite or crash a mosquito population. Gene drives based on homing endonucleases have been demonstrated in the laboratory in transgenic populations of mosquitoes and fruit flies. These enzymes could be used to drive alterations through wild populations.」の詳細全文を読む
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